The Najt Lab

Research in the Najt laboratory focuses the comprehensive understanding of lipid metabolism, with an emphasis on how alterations in the genes and metabolites in this network contribute to human diseases such as Alzheimer’s disease, non-alcoholic/metabolic fatty liver disease (NAFLD/MASLD), hepatic insulin resistance, cardiovascular disease, and Type 2-Diabetes and how these diseases impact healthspan. Our studies span a range of disciplines that ultimately link nutrition, exercise physiology, biochemistry and physiology. In other words, the lab studies metabolism on a global level. 

An important goal of the laboratory is to do research that helps us identify detailed mechanisms of disease and aging using animal and cell models and then translate these findings to the clinic. Ultimately, we hope that by advancing our knowledge into the basic metabolism of nutrients we will come closer to understanding how metabolic diseases develop and, therefore, will be better equipped to identify new preventions or treatments.