Publications from the Najt Lab

Research Articles

Najt CP, Adhikari A, Heden TD, Gansemer ER, Rauckhorst AJ, Cui W, Markowski TW, Higgins L, Kerr EW, Boyum MD, Alvarez J, Brunko S, Mehra D, Puchner EM, Taylor EB, Mashek DG. Organelle interactions compartmentalize hepatic fatty acid trafficking and metabolism. Cell Reports 2023;42:112435.

Shang L, Aughey E, Kim H, Heden TD, Wang L, Najt CP, Esch N, Brunko S, Abrahante JE, Macchietto M, Mashek MT, Fairbanks T, Promislow, Neufeld TP, Mashek DG. Systemic lipolysis promotes physiological fitness in Drosophila melanogaster. Aging 2022;14(16):6481-6506.

Heden TD, Chen C, Leland G, Mashek MT, Najt CP, Shang L, Chow LS, Mashek DG.  Isolated and combined impact of dietary olive oil and exercise on markers of health and energy metabolism in female mice. Journal of Nutritional Biochemistry 2022;107:109040.

Najt CP, Khan SA, Heden TD, Witthuhn BA, Perez M, Mead LE, Franklin MP, Karanja KK, Graham MJ, Mashek MT, Bernlohr DA, Parker L, Chow LS, Mashek DG. Lipid droplet-derived monounsaturated fatty acids traffic via PLIN5 to allosterically activate SIRT1. Molecular Cell 2020;77(4):810-824.

Muratore KA, Najt CP, Livezey NM, Marti J, Mashek DG, Arriaga EA. Sizing lipid droplets from adult and geriatric mouse liver tissue via nanoparticle tracking analysis. Analytical and bioanalytical chemistry 410, 3629-3638.

Najt CP, Senthivinayagam S, Aljazi MB, Fader KA, Olenic SD, Brock JRL, Lydic TA, Jones AD, Atshaves BP. Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis. American Journal of Physiology-Gastroinestinal and Liver Physiology 2016;310(9)G726.

Najt CP, Lwande JS, McIntosh AL, Senthivinayagam S, Gupta S, Kuhn LA, Atshaves BP. Structural and functional assessment of perilipin 2 lipid binding domain(s). Biochemistry 2014;53(45)7051-7066.

Review Articles

Najt CP, Devarajan M, Mashek DG. Perilipins at a glance. Journal of Cell Science 2023;135(5):jcs259501.

Seibert JT, Najt CP, Heden TD, Mashek DG, Chow LS. Muscle Lipid Droplets: Cellular Signaling to Exercise Physiology and Beyond. Trends in Endocrinology and Metabolism 2020;31(12):928.

Guerrero CR, Maier LA, Griffin TG, Higgins L, Najt CP, Perlman DM, Bhargava M. Application of proteomics in sarcoidosis. American Journal of Respiratory Cell and Molecular biology 2020;63(6):727.

You can find a complete list of publications available via PubMed